The National Institutes of Health recently awarded Cleveland Clinic's Jacob Scott, M.D., D.Phil., and collaborators $2.8 million to translate research on how cancer cells evolve and compete into patient care.
Reviewed by Lily Ramsey, LLMAug 22 2023 The project aims to move previous advances done in vitro closer to clinical reality by developing computer and preclinical models side-by-side, a significant step in the fight against multidrug-resistant cancers that are responsible for more than 90% of cancer deaths.
Computational models are the "bridge" necessary to study these models in patients, said Dr. Scott, a radiation oncologist and head of Translational Hematology & Oncology Research's Theory Division at Cleveland Clinic. Treating cancer is a months-long process, so time is a challenge in collecting the data necessary for clinical application.
Dr. Scott is co-principal investigator with Andriy Marusyk, Ph.D., a long-time collaborator at Moffit Cancer Center. Another collaborator is Emily Dolson, Ph.D., former post-doctoral fellow in Dr. Scott's lab and now an assistant professor at Michigan State University.
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