A randomized trial involving all hospitals in London, U.K., has found no difference in survival at 30 days in patients with resuscitated cardiac arrest in the community who were taken by ambulance to a cardiac arrest center compared with those delivered to the geographically closest emergency department. That's the finding of late breaking research presented in a Hot Line session August 27 at ESC Congress 2023. The study also found no overall difference in neurological outcomes at discharge and at three months between groups.
A randomized trial involving all hospitals in London, U.K., has found no difference in survival at 30 days in patients with resuscitated cardiac arrest in the community who were taken by ambulance to a cardiac arrest center compared with those delivered to the geographically closest emergency department. That's the finding of late breaking research presented in a Hot Line session August 27 at
The ARREST trial investigated whether expedited transfer of OHCA patients to a cardiac arrest center reduces mortality compared with delivery to the closest emergency department. The trial also examined whether there was any difference in neurological outcomes with the two strategies. This was a randomized controlled trial conducted pre-hospital across the whole of London examining a pathway of care.
The primary endpoint was all-cause mortality at 30 days in the intention-to-treat population. Secondary endpoints included all-cause mortality at three months and neurological outcomes at discharge and three months, assessed by the modified Rankin scale and cerebral performance category score. The primary outcome of 30-day all-cause mortality occurred in 258 of 411 patients in the cardiac arrest center group and 258 of 412 patients in the standard care group . There was no difference in the secondary endpoint of three-month all-cause mortality between the two groups . Neurological outcomes were similar at hospital discharge and three months for both the modified Rankin scale and CPC score .
Belgique Dernières Nouvelles, Belgique Actualités
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