Are irregular sleep patterns associated with increased mortality risk?

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Are irregular sleep patterns associated with increased mortality risk?
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Researchers examined whether sleep regularity is associated with an increased risk of all-cause, cardiovascular disease (CVD), and cancer mortality.

By Neha MathurAug 22 2023Reviewed by Sophia Coveney In a recent article posted to the medRxiv* server, researchers recruited 8,975 adults aged 40 to 69 years from the United Kingdom Biobank for a prospective analysis of their sleep regularity and risk of all-cause, cardiovascular disease , and cancer mortality.

Exposure to artificial and blue light at night, shift work, and erratic 24/7 lifestyles have blurred the day and night distinction, exacerbating the disruption of circadian rhythm manifold and heightening the need for research in this area. This software uses an algorithm to determine the time window between the onset and end of daily sleep, during which bouts of sustained inactivity are considered sleep.

Finally, they used a Cox proportional hazards model to examine associations between the SRI and all-cause, CVD, and cancer-related mortality. They also used time hazards models depicting time-varying hazard ratios for interaction between SRI and time aggregated into three-month intervals. Mortality rates were highest for people with the most irregular sleep pattern and declined almost linearly as sleep regularity attained average levels, after which this reduction began to plateau.

Furthermore, the study results demonstrated that the SRI encompassed information about mortality risk beyond what is suggested by the standard deviation metrics of sleep onset and duration.

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