A randomized trial involving all hospitals in London, UK, has found no difference in survival at 30 days in patients with resuscitated cardiac arrest in the community who were taken by ambulance to a cardiac arrest center compared with those delivered to the geographically closest emergency department.
Reviewed by Lily Ramsey, LLMAug 28 2023 That's the finding of late-breaking research presented in a Hot Line session today at ESC Congress 2023. The study also found no overall difference in neurological outcomes at discharge and at three months between groups.
The ARREST trial investigated whether expedited transfer of OHCA patients to a cardiac arrest center reduces mortality compared with delivery to the closest emergency department. The trial also examined whether there was any difference in neurological outcomes with the two strategies. This was a randomized controlled trial conducted pre-hospital across the whole of London examining a pathway of care.
Between 15 January 2018 and 1 December 2022, 862 patients were enrolled, of whom 431 were randomly assigned by London Ambulance Service paramedics to expedited transfer to a cardiac arrest center and 431 to standard care. Some 32% of participants were women.
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