A Review published in Diabetology & Metabolic Syndrome finds that the risk of type 2 diabetes is elevated in individuals with a high neck circumference. Also, pregnant women with high neck circumference have higher odds of gestational diabetes.
]. Considering the inconsistencies in the findings of existing studies, a systematic review and meta-analysis of observational epidemiological studies were performed to evaluate the association between NC and the risk of DM.The present systematic review and meta-analysis were conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analysis statement [].
The assessment tool involving 11 items, as recommended by the Agency for Healthcare Research and Quality, was applied for cross-sectional studies []. The quality of the studies was first evaluated with reference to the established questions and then scored according to the following criteria: 1 point = if the item was considered in the study and 0 points = if the item was not considered or this aspect was ambiguous.
Each study was rated independently by two authors . Any disagreements were resolved via discussion with a third investigator .We considered OR as the common measure of association between the NC and the risk for DM. The reported RR was considered approximately as the OR. We calculated an overall pooled OR by using a random-effects model for the main analysis [
]. If studies reported results separately for different subgroups, we combined the subgroup estimates by using fixed-effect models before inclusion in the main meta-analysis.statistic were applied to test the heterogeneity. Thestatistic measures the percentage of total variation across studies because of heterogeneity rather than because of chance.
Belgique Dernières Nouvelles, Belgique Actualités
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