Can smoking cigarettes alter your bone structure? SciReports usponline cigarette smoking tobacco bone structure bonestructure research
By Dr. Chinta SidharthanMay 2 2023Reviewed by Lily Ramsey, LLM In a recent study published in the Scientific Reports Journal, researchers conducted in situ analyses of tissue samples from individuals who smoked, were former smokers, or never smoked to understand the mechanisms through which exposure to cigarette smoke causes alterations in bone structure.
The osteoblastic lineage cells and the osteoclasts are the two specialized bone tissue cells that maintain homeostasis. About the study In the present study, the researchers used femoral head tissue samples from individuals undergoing total hip arthroplasty surgery after obtaining informed consent from the participants.
The tissue samples were categorized into three groups based on smoking status: smokers, former smokers, and non-smokers; they were analyzed using histological staining with hematoxylin and eosin and quantified to determine trabecular volume. In contrast, the percentage of collagen type V was higher in the tissue samples from smokers than that from non-smokers. Additionally, although the evaluation of RANKL levels did not show a significant difference between the groups, the OPG levels in the tissue from smokers were lower than that from non-smokers.
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