Certain gut problems, such as constipation, difficulty swallowing, and irritable bowel syndrome (IBS), may be early warning signs of the neurological condition Parkinson's disease, suggests research published online in the journal Gut.
Gastrointestinal symptoms are thought to precede the development of cerebrovascular disease, such as stroke or a brain aneurysm, or Alzheimer's disease, and it has been suggested that gut conditions may precede the development of Parkinson's disease too.
The researchers then tested the same hypothesis, but in a different way, by dividing all the adults in the network who had been diagnosed with any of 18 gut conditions into separate groups-;one for each condition of interest. Specifically, gastroparesis , dysphagia , and constipation were all associated with a more than doubling in risk of Parkinson's disease in the 5 years preceding the diagnosis, while IBS without diarrhoea was associated with a 17% higher risk.
Some other gut issues, including functional dyspepsia ; IBS with diarrhoea; and diarrhoea plus faecal incontinence, were also more prevalent among people who developed Parkinson's disease.
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