Chemotherapy drug reaches brain in humans for first time northwesternu TheLancetOncol
The four-minute procedure to open the blood-brain barrier is performed with the patient awake, and patients go home after a few hours. The results show the treatment is safe and well tolerated, with some patients getting up to six cycles of treatment.
"This is potentially a huge advance for glioblastoma patients," said lead investigator Dr. Adam Sonabend, an associate professor of neurological surgery at Northwestern University Feinberg School of Medicine and a Northwestern Medicine neurosurgeon. "There is a critical time window after sonification when the brain is permeable to drugs circulating in the bloodstream," Sonabend said.
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