Does irritable bowel syndrome result from gravity? CedarsSinai Gravity IBS
By Tarun Sai LomteDec 5 2022Reviewed by Aimee Molineux In a recent study published in the American Journal of Gastroenterology, the author proposed and discussed the hypothesis that irritable bowel syndrome may result from gravity.
The author posited that IBS susceptibility is determined by three factors of the g-force: resistance, detection, and vigilance. G-force resistance governs the ability of the GI tract to resist gravity, detection defines the ability of the peripheral nervous system to detect gravity strain on somatic and visceral structures, and vigilance determines the readiness of the central nervous system to predict and prevent dangerous g-force events.
Moreover, the large intestine is supported by three strips of smooth muscle traversing throughout the colon, namely the taenia coli. Together, the taenia coli and mesentery suspend, bolster, strengthen, and protect the GI tract. If these resistance mechanisms become ineffective, GI distress and IBS may result.
Related StoriesAcute pain can become chronic over time through central sensitization. Back pain is reported by up to 80% of IBS patients. Anti-gravity extensor muscles are constantly strained to support the abdominal load under the pull of gravity. If the spine fails, then the crane will sag, leading to angulation of the mesenteric root and disruption of visceral function.
There is substantial evidence suggesting that IBS patients develop peripheral sensitization. The g-force strain on support structures of the GI tract causes the overproduction of nociceptive mediators, triggers afferent neurons, and leads to PNS sensitization. Abnormal serotonin levels have been long implicated in IBS, and variations in serotonin biology can have profound effects throughout the body.
G-force vigilance Some individuals show greater resilience to g-forces than others. For instance, some people may experience amusement while dropping from the rollercoaster, whereas others may be threatened and vulnerable. These represent the two extremes of the g-force vigilance factor. Gut feelings can be pathologic when the g-force perilously deviates from the normal limits, and the chances of its occurrence are improbable or impossible.
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