Does previous antibiotic treatment affect COVID-19 severity? eClinicalMed OfficialUoM UniversityLeeds UniofOxford COVID19 coronavirus covid antibiotics antibiotic
By Neha MathurJul 12 2023Reviewed by Benedette Cuffari, M.Sc. In a recent article published in eClinical Medicine, researchers determine whether frequent antibiotic use increased the risk of adverse outcomes, including death, following severe acute respiratory syndrome coronavirus 2 infection.
About the study In the present population-level matched case-control study, researchers create two distinct cohorts to examine the long-term effects of repeated and intermittent antibiotic use on subsequent COVID-19 severity. Related StoriesIn Study 2, the severity of outcomes was determined among COVID-19-related hospitalizations identified in Study 1 by measuring the number of deaths.
Quintile groups were created based on the number of prior antibiotic prescriptions to indicate the frequency of previous antibiotic exposure. For example, the first and fifth quintiles represented low- and high-frequency users. Based on the type of antibiotic prescribed, each quintile was further divided into one to three groups.
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