Exploring effects of COVID-19 pandemic on neurodevelopment and mental health in adolescents Stanford COVID19 SARSCoV2 Neurodevelopment MentalHealth
By Tarun Sai LomteDec 5 2022Reviewed by Aimee Molineux In a recent study published in Biological Psychiatry: Global Open Science , researchers examined the impact of the coronavirus disease 2019 pandemic on adolescents' neurodevelopment and mental health.
About the study In the present study, researchers analyzed the effects of the COVID-19 pandemic on adolescents' mental health and neurodevelopment. They included 163 adolescents from the San Francisco Bay Area who were participants in a longitudinal analysis investigating the effects of stress in early life on psychobiology.
Genetics & Genomics eBook Compilation of the top interviews, articles, and news in the last year. Download a free copy A subset of participants underwent magnetic resonance imaging . Based on the cortical and sub-cortical features, the brain age gap estimate was computed using sex-specific ML models created by the Enhancing Neuroimaging Genetics through Meta-Analysis -Brain Age working group. BrainAGE was calculated as the difference between the chronological and predicted age of the brain.
There were no differences in externalizing symptoms between the two groups. The MANOVA test on brain metrics showed significant differences between pre- and peri-COVID-19 adolescents. Peri-COVID-19 adolescents had decreased cortical thickness and larger bilateral hippocampal and amygdala volumes. Moreover, peri-COVID-19 adolescents had an older BrainAGE than pre-COVID-19 peers.
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