How are genetics, lifestyles, and cardiovascular and thromboembolic events associated following COVID-19 diagnosis? NatureComms genetics lifestyles cardiovascular thromboembolic covid COVID19 SARSCoV2
By Tarun Sai LomteAug 7 2023Reviewed by Sophia Coveney A recent study published in Nature Communications evaluated the associations between host genetics, lifestyle factors, and cardiovascular and thromboembolic events after coronavirus disease 2019 .
About the study In the study, researchers assessed the associations between lifestyle factors, host genetics, and the risk of CVEs following COVID-19 diagnosis. Cox proportional hazard models assessed associations of each PRS for CVE with the corresponding post-COVID-19 complication. The associations were additionally evaluated in sub-groups of age, sex, body mass index , ethnicity, recent anti-thrombotic medication, and severe acute respiratory syndrome coronavirus 2 infection type .
Related StoriesIn total, 1,397 AF, 244 VTE, 104 ISS, and 733 CAD events were reported during the 90-day follow-up after COVID-19. The incidence rates were 4.14 for ISS, 9.73 for VTE, 29.3 for CAD, and 56.05 for AF per 1000 person-years. The cumulative incidence of most CVEs increased dramatically within 30 days post-COVID-19 and flattened afterward.
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