How does prenatal exposure to phthalates, organophosphate esters, and organophosphorus pesticides influence children’s language ability? UNC DukeU Folkehelseinst children child childhealth pesticides language
By Tarun Sai LomteFeb 22 2023Reviewed by Danielle Ellis, B.Sc. In a recent study published in Environmental Research, researchers examined the effects of prenatal exposure to chemicals on early child language ability.
The study population for the present analysis was drawn from nested MoBa sub-studies, which focused on attention-deficit/hyperactivity disorder . The authors leveraged 1) a preschool ADHD sample in which parents indicated ADHD-like symptoms of their children, which was later assessed onsite, 2) ADHD cases from the National Patient Registry , and 3) a random sample from MoBa regardless of ADHD-like symptoms.
Genetics & Genomics eBook Compilation of the top interviews, articles, and news in the last year. Download a free copy Structured equation modeling was applied to examine the effects of phthalates, OPEs, and OPs on child communication at 18 months and expressive language at preschool age. In addition, sensitivity analyses were performed to study associations between prenatal chemical exposure and child communication at 18 months.
The OP factor showed high loadings of diethyl phosphate and dimethyl phosphate , while the OPE factor showed high loadings of di-n-butyl phosphate and diphenyl phosphate . Metabolites within chemical families had greater correlations than between families. Prenatal exposure to OPs was associated with lower communication at 18 months.
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