My dad never found treatment for his Alzheimer's. His brain is now helping solve that problem for other patients, writes Rebecca Leventhal
Regardless, Aduhelm was not suitable for my father, who, by the time of its approval, had progressed to advanced Alzheimer’s, past the point where scientists believe amyloid removal might be effective.
As his Alzheimer’s progressed, we struggled to offer him appropriate support. He grew frustrated, unable to work around his new limitations. We’d find him jiggling a broken hinge, aware it needed to be fixed but unable to identify a solution. In that moment, I’d feel a sharp pang in my chest—one of pain and pride; I loved that he was still a problem solver, and I wanted to support him in solving this particular one.
Knowing nothing about brain donation, I googled “brain donation” and saw a list of places that accepted brain tissue. I pictured my dad’s unaccompanied brain being sent across the country in a padded envelope to a lab that I didn’t know. I felt like we’d be abandoning him. I dropped the topic. In the years my dad was sick, no one suggested brain donation. I imagine it is impossibly hard for a medical professional to bring up the topic. My sisters and I do not know why we thought of it except, perhaps, that the act of watching my dad die made us ask ourselves, “Is there something we should be doing?”
I asked Seth to connect me to the brain donation team. Andrew Stern, a physician-scientist in the Selkoe Lab, called me to talk about logistics.
Belgique Dernières Nouvelles, Belgique Actualités
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