The victim, found stabbed in Huddersfield early on Monday, is believed to have been targeted.
Three arrests have been made following the death of a 17-year-old boy in a "targeted" stabbing in Huddersfield, police have said.
Det Ch Insp Alan Weekes, of the Homicide and Major Enquiry Team, said: "Officers are carrying out a number of fast-moving enquiries following a very serious incident in Huddersfield today in which a young man has lost his life.
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