The experts weigh in on Berberine 🙌
On the other hand, berberine activates an enzyme known as AMPK that plays a key role in regulating metabolism and controlling how our bodies use energy at a cellular level. “AMPK is involved in managing blood sugar levels, insulin signalling, food intake and body weight," adds Rhian.Berberine causes different chemical reactions within our bodies' cells.
As with any supplement or medication, there is always the potential for sensitivity or an allergic reaction. That said, “berberine is generally considered a safe and well-tolerated botanical medicine by the German Commission E, which is one of the most widely accepted committees on botanical safety,” Rhian says.
Physically, you run into problems when you start overdosing. Some TikTokers are advocating a dosage of 5 grams of berberine per day, which is irresponsible and unsafe. “At higher doses, individuals may experience side effects, which include diarrhoea, abdominal pain, dizziness and flatulence; however, side effects are uncommon at normal doses,” Rhian notes.
There are also psychological considerations when the popular narrative around a health supplement changes. When its sole benefit is suddenly pegged off of weight loss, it can be triggering for those who are suffering with an eating disorder or have done so in the past, says, who is both an aesthetic doctor, a trained psychiatrist and a member of the Royal College of Psychiatry. It can also set you on a dangerous dieting cycle in much the same way as those ‘natural’ diet teas in the '00s.
“When talking about weight loss there is always the risk of missing the point of healthy eating patterns and a healthy lifestyle," says Dr Galyna. "Healthy doesn’t mean skinny. Incorporating a variety of nutrient-dense foods, engaging in regular physical activity and adopting healthy habits are what can contribute to long-term wellbeing.”“Those who are pregnant or breastfeeding, and also children should avoid berberine,” says Lola.
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