Researchers performed a meta-analysis to evaluate the incidence of cardiovascular (CV) events among individuals with insomnia.
By Pooja Toshniwal PahariaSep 26 2023Reviewed by Danielle Ellis, B.Sc. In a recent study published in PLoS ONE, researchers performed a meta-analysis to evaluate the incidence of cardiovascular events among individuals with insomnia.
Databases such as PubMed/MEDLINE, Cochrane Library, and Google Scholar were searched through August 2022 for studies comparing predefined CV outcomes among insomniac individuals. The primary study outcomes were MI and CV mortality, whereas secondary study outcomes included any-cause deaths and cardiovascular disease incidence.
Studies conducted on animals and children, records such as case-control studies, case reports, and case series, and studies lacking comparators or controls were excluded from the analysis. The Newcastle-Ottawa Scale was used to assess the quality of evidence. The researchers performed a sub-group analysis to evaluate the associations of CVD outcomes by follow-up duration. In addition, sensitivity analyses were performed for records with I2 values exceeding 50.
In the sub-group analysis, analyzing for 10 to 20 years of follow-up, any-cause deaths were significantly higher among individuals with insomnia versus those without . Consistent trends were observed with the overall results at 10 to 20 years, revealing significantly greater incidences of cardiovascular events among insomniacs versus non-insomniacs .
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