Is platelet-rich plasma therapy beneficial in treating chronic respiratory disease? CureusInc MUA_Medicine LARKINHOSPITAL respiratorydisease disease chronicdisease lungs plasmatherapy therapy
By Dr. Chinta SidharthanJan 4 2023Reviewed by Danielle Ellis, B.Sc. In a recent study published in the journal Cureus, researchers conducted a literature review to determine whether platelet-rich plasma therapy could help slow disease progression through lung regeneration in patients with chronic respiratory disease.
While tobacco smoking is the predominant trigger for COPD, genetic causes, abnormal lung development during childhood, and occupational exposure to substances can also cause chronic bronchitis and emphysema. Current research on COPD treatment is exploring the use of mesenchymal stem cell therapy in lung regeneration. Although mesenchymal stem cells are a promising option, obtaining mesenchymal stem cells is either painful and invasive through adipose tissue and bone marrow or controversial when procured from embryonic or umbilical cord tissue.
Review findings The present review aimed to evaluate existing literature for evidence on the benefits of using platelet-rich plasma to regenerate lung tissue in patients with chronic respiratory disease. The review included various types of studies on human patients as well as animal models and patients.
Furthermore, a randomized controlled trial on platelet-rich plasma therapy for smoke inhalation patients showed a decrease in the length of intubation days and hospital stays, as well as mortality rates.
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