Italian study evaluates COVID-19 reinfection risk among previously infected and vaccinated individuals UniAvogadro researchsquare COVID19 SARSCoV2 Vaccination Infection
By Dr. Chinta SidharthanOct 31 2022Reviewed by Aimee Molineux In a recent study posted to the Research Square* preprint server, a team of researchers from Italy investigated the risk of severe acute respiratory syndrome coronavirus 2 reinfection and hospitalization among individuals with vaccinations and previous SARS-CoV-2 infections.
However, with the emergence of SARS-CoV-2 Omicron subvariants containing mutations in the spike protein regions that enable immune evasion, the efficacy of hybrid immunity against reinfections needs to be evaluated. The first case study evaluated the risk of infection among 31,832 individuals whose nasopharyngeal swabs tested positive for SARS-CoV-2. In contrast, the second case study estimated the hospitalization risk among 911 patients admitted at the LSU with COVID-19. Each patient was matched with four controls of the same sex and age who did not have SARS-CoV-2 infections or were not hospitalized at the index date of each case study.
Results The results indicated that when vaccinations and previous infections were evaluated independently, vaccination reduced the risk of infections by 36% and the risk of hospitalization by 89%. Prior SARS-CoV-2 infections reduced reinfection and hospitalization risks by 65% and 90%, respectively. Vaccinated individuals with previous SARS-CoV-2 infections were at 62% and 98% lower risk of reinfections and hospitalizations, respectively.
The Omicron variants had a significant effect in reducing the immunity induced by vaccinations and previous infections. After the emergence of the Omicron variant, the risk of disease among vaccinated individuals went from 43% to 67%. Unvaccinated, previously infected individuals exhibited a 45% reduction in reinfection risk after the Omicron variant’s emergence, compared to the 89% risk reduction seen before Omicron became prevalent.
Belgique Dernières Nouvelles, Belgique Actualités
Similar News:Vous pouvez également lire des articles d'actualité similaires à celui-ci que nous avons collectés auprès d'autres sources d'information.
Favorable outcomes of infants born after maternal COVID-19 during pregnancyFavorable outcomes of infants born after maternal COVID-19 during pregnancy Coronavirus Disease COVID Pregnancy aap_peds
Lire la suite »
Effects of SARS-CoV-2-associated stress among pregnant women on development of fetus brainEffects of SARS-CoV-2-associated stress among pregnant women on development of fetus brain Brain SARSCoV2 Stress Coronavirus Disease COVID Neurology medrxivpreprint ChildrensLA PittTweet KeckMedUSC
Lire la suite »
Estimating the risk of airborne SARS-CoV-2 transmission in a train carriageEstimating the risk of airborne SARS-CoV-2 transmission in a train carriage Coronavirus Disease COVID PublicHealth imperialcollege Cambridge_Uni UniOfSurrey QinetiQ
Lire la suite »
SpyCatcher-SpyTag technology used to develop recombinant protein-based intranasal vaccine against SARS-CoV-2The findings of a new study showed that the intranasal SpyCage vaccine platform can be protective against SARS-CoV-2 and may prove to be a versatile and adaptable modality for the formulation of intranasal vaccines that target respiratory pathogens.
Lire la suite »
What is the impact of SARS-CoV-2 on HIV-1 infectivity?In a new study, researchers assessed the effect of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and SARS-CoV envelope (E) proteins on human immunodeficiency virus type 1 (HIV-1) infectivity.
Lire la suite »
Scientists dispute a suggestion that SARS-CoV-2 was engineeredOn October 20th an un-peer-reviewed “preprint” was published, claiming to show that SARS-COV-2 is the product of genetic engineering. Other researchers are now weighing in with criticisms
Lire la suite »