Weight-loss drugs will change lives, writes Swiss Re’s chief medical officer in a guest essay. But they come “with strings attached”
have come on the market or are likely to be approved soon. From Big Pharma to biotechs, a bevy of firms are either selling such medicines or running trials.
Anyone thinking of taking these medicines needs to consider some important caveats. GLP-1 drugs come with side-effects that include nausea, dyspepsia, abdominal distension and reflux, though these often diminish over time. About 7% of people in one trial ended treatment because of side-effects, compared with 3.1% in the placebo group.
If these drugs are destined to be used by individuals for decades, side-effects are also likelier to accumulate. Lifelong treatments have big financial implications, too. The annual price of injections has been pegged at as much as $13,600 in AmericaEven if the price falls as competition intensifies, anti-obesity drugs could prove very costly for public insurance programmes, should they be required to cover them.
Two of the most important such interventions relate to what we eat and how much we exercise. Much of what we consume today looks nothing like what our ancestors put on their plates, skewed as it is towards processed food. Life is also growing more automated, meaning less physical labour and more sedentary lifestyles.
Belgique Dernières Nouvelles, Belgique Actualités
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