New animal research suggests that little-studied brain cells known as astrocytes are major players in controlling sleep need and may someday help humans go without sleep for longer without negative consequences such as mental fatigue and impaired physical health.
"Our findings suggest that our need for sleep isn't just a function of prior wake time but is also driven by these long-ignored non-neuronal cells," said first author Ashley Ingiosi, an assistant professor of neuroscience at Ohio State University who conducted the study while working as a postdoctoral research associate in Frank's lab at WSU.
Next, the researchers plan to conduct behavioral tests in mice to determine how activating basal forebrain astrocytes to induce wakefulness might impact other processes besides sleep need, such as attention, cognition, learning, memory, metabolism and immune function. To get at least some indication of the potential impact on attention and cognition, they looked at EEG markers of those two processes in this study and found them to be similar to those seen in well-rested controls.Ashley M.
Belgique Dernières Nouvelles, Belgique Actualités
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