Expectations from the scene are that police will be conducting a collision investigation and the closure is expected to remain in place for several hours
Access to the M6 via the M55 is also closed because of the same incident. Motorists are being asked by Lancashire Police to avoid the area and seek alternative routes wherever possible.
Traffic monitoring service Inrix said: "M6 Southbound closed due to overturned vehicle from J32 M55 to J31 A59 Preston New Road ." It added: "M6 Southbound exit slip road closed due to overturned vehicle at J31 A59 Preston New Road (This is an unfolding incident. We will bring you updates and diversion information below.
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