Researchers find evidence for 'substantial' monkeypox transmission before symptoms appear bmj_latest
today has found evidence for"substantial" monkeypox transmission before symptoms appear or are detected .
Although case numbers are now declining, it's still important to understand the"transmission dynamics" of the virus—for example, how it spreads from one person to another and how quickly symptoms appear—to help inform policy decisions and future interventions. Their findings are based on routine surveillance and contact tracing data for 2,746 individuals who tested positive for monkeypox virus in the UK between May 6 and August 1, 2022. Their average age was 38 years and 95% reported being gay, bisexual, or men who have sex with men.To estimate this, they linked information on exposure and symptom onset dates from these individuals to their contacts through contact tracing case questionnaires, which they then analyzed using two statistical models.
Analysis of individual level patient data, collected from a subset of patients with more detailed information, seemed to confirm this explanation, with 10 out of 13 case-contact patient pairs reporting pre-symptomatic transmission. Four days was the maximum time that transmission was detected before symptoms appeared.
Nevertheless, this was a large study using robust methods and adjusting for key biases that are present in the data, providing greater confidence in the conclusions.
Belgique Dernières Nouvelles, Belgique Actualités
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