Risk of ALCL Following Postmastectomy Implant Reconstruction in Women With Breast Cancer and DCIS

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Risk of ALCL Following Postmastectomy Implant Reconstruction in Women With Breast Cancer and DCIS
Belgique Dernières Nouvelles,Belgique Actualités
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Breastimplants after mastectomy associated with very low risk of lymphoma ColumbiaMed jamanetworkopen

< .05 was considered statistically significant.We identified 56 784 women who received postmastectomy implant reconstruction . The sample included 7% Asian or Pacific Islander women, 8% Black women, and 84% White women. The median follow-up time was 81 months, including 15 765 women with follow-up times of at least 10 years. Five cases of breast ALCL were diagnosed over 421 223 person-years. The observed vs expected incidence rates were 11.9 vs 0.3 per million persons per year .

Patients with breast cancer who are eligible for mastectomy should be counseled on the risks of breast ALCL after implant reconstruction. However, based on these results, we do not believe that women should be dissuaded from pursuing implant-based reconstruction due solely to the risk of ALCL.

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