Exposure to environmental chemicals, including those in common plastic products, has been linked with an increased risk of cardiovascular disease, or CVD, the leading cause of death worldwide. According to the World Health Organization, 17.9 million people died from CVDs in 2019.
Changcheng Zhou, a professor of biomedical sciences in the School of Medicine at the University of California, Riverside, has received an eight-year award of nearly $6.8 million from the Revolutionizing Innovative, Visionary Environmental Health Research program of the National Institute of Environmental Health Sciences, or NIEHS, to investigate how interactions between genes and endocrine disrupting chemicals, or EDCs, may increase CVD risk.
EDCs mimic, block, or interfere with the body's hormones. They can affect reproduction and the functioning of the immune and nervous systems. They are also known to increase cancer risk. Examples are human-made chemicals used as industrial solvents/lubricants and their byproducts, as well as some plastics, pesticides, fungicides, and pharmaceutical agents. Other examples are some natural chemicals, such as phytoestrogens , found in human and animal food.
I am humbled and honored to receive the NIEHS RIVER grant, which provides the flexible and long-term support my research program needs to conduct innovative and impactful research in an area of crucial importance to the NIEHS mission. We expect the research this grant supports will contribute to the understanding of gene-EDC interactions in predisposing individuals and their children to CVD.
Zhou's prior work showed many EDCs activate a sensor in cells, called the pregnane X receptor, or PXR, which detects foreign chemicals and substances and helps regulate atherosclerosis development. The new funding will allow Zhou to study the mechanisms that allow EDCs to affect PXR in cells, leading to atherosclerosis.
Belgique Dernières Nouvelles, Belgique Actualités
Similar News:Vous pouvez également lire des articles d'actualité similaires à celui-ci que nous avons collectés auprès d'autres sources d'information.
European Gas Price Spike Highlights Painful Exposure To Global MarketsDespite high gas inventories, European natural gas prices remain vulnerable to global supply disruptions, making the continent more vulnerable to price shocks.
Lire la suite »
Scientist issues urgent Covid warning over 'bad news' just weeks awayIt comes amid a spike in new variant BA.6 infections.
Lire la suite »
Scientist issues urgent Covid warning over 'bad news' just weeks awayIt comes amid a spike in new variant BA.6 infections.
Lire la suite »
The autumn nail trends to know for 2023, according to the prosCheck out the autumn nail trends to know for 2023, according to the pros: 🍁💅
Lire la suite »
Top spots to check out on a flying visit to Belfast according to The TimesThere is something for everyone in our wee city
Lire la suite »
MW3 set to bring back classic 'red dot' mini map and fans are relievedMW3 set to bring back classic “red dot” mini map ModernWarfare3 ModernWarfareIII CallofDutyModernWarfare
Lire la suite »