A simple blood test may predict the risk of progressive heart and kidney disease in people with type 2 diabetes and kidney disease, according to new research published in the journal Circulation.
) trial to assess the effects of canagliflozin on concentrations of the four biomarkers from the study start, the one-year mark and the three-year mark.
The concentrations of each of the four biomarkers in people taking canagliflozin were lower after one year and three years compared to those taking the placebo. "It was reassuring to discover that canagliflozin helped reduce risks the most in people with the highest chances for complications. Future studies are needed to better understand how type 2 diabetes in conjunction with kidney disease develops and progresses so that we may initiate life-saving therapies earlier, before symptoms of heart and kidney disease have occurred," Januzzi said.
The study was limited in that not all study participants in the CREDENCE trial had available samples for biomarker measurement, and the participants with biomarker measurement may not be representative of the study's entire population. Additionally, biomarker data over time were not complete, and some study participants had missing values during the study follow-up period.
Belgique Dernières Nouvelles, Belgique Actualités
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