A new study led by researchers at The Ohio State University Wexner Medical Center and College of Medicine shows the benefit of having patients with advanced disease from dilated cardiomyopathy (DCM) undergo genetic testing to help identify the inherited heart muscle disease in family members.
who carry the same gene mutations and start treatment with early signs of disease before the individual has advanced disease," said senior author Ray Hershberger, MD, a cardiologist and division director of Human Genetics at the College of Medicine.DCM happens when the heart muscle weakens and the left ventricle enlarges. It can occur in family members at almost any age but the typical onset is mid 40s.
Dilated cardiomyopathy is the most common cause of patients needing a heart transplant and is responsible for up to half of the heart failure cases that result from a weakened left ventricle. Symptoms include shortness of breath with exertion, fatigue, edema of the legs and feet, an irregular heartbeat and lethal arrhythmias.
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