An important step toward next-generation probiotics
Participants
Participating volunteers were recruited through advertising in social media and through posters in public areas . Participants who met all inclusion criteria , lacked all exclusion criteria , had normal blood biochemistry, blood pressure and heart rate, were invited to participate.The primary outcome was tolerability and was tested using discontinuation due to investigational product during 8 weeks of treatment.
At the randomization visit, faecal samples were collected and GSRS was completed in order to collect information of any gastrointestinal symptoms the preceding week. All participants received a diary for recording daily doses taken and to make notes about any potential adverse events. During study visits three to five, faeces and blood samples as well as data from the GSRS questionnaire form were collected.
Belgique Dernières Nouvelles, Belgique Actualités
Similar News:Vous pouvez également lire des articles d'actualité similaires à celui-ci que nous avons collectés auprès d'autres sources d'information.
An eco-lodge in Uganda’s tropical forest invites guests to commune with natureAn eco-lodge by Uganda-based multidisciplinary design studio Localworks, offers rare, sustainability-minded experiences in the country's tropical forests
Lire la suite »
Anatomical and functional maturation of the mid-gestation human enteric nervous system - Nature CommunicationsDershowitz and colleagues assess second trimester human fetal enteric nervous system development and function. They describe structural reorganization of the enteric nervous system that corresponds to gastrointestinal motility onset in ex vivo preparations.
Lire la suite »
An electrogenetic interface to program mammalian gene expression by direct current - Nature MetabolismHuang et al. develop an interface to allow electrode-mediated stimulation of gene expression in human cells, utilizing direct current-generated reactive oxygen species to stimulate transgene expression downstream of the KEAP1–NRF2 biosensor. In a type 1 diabetic mouse model, this interface is demonstrated to ameliorate hyperglycemia by stimulating insulin expression.
Lire la suite »
The role of transcription factors in shaping regulatory T cell identity - Nature Reviews ImmunologyRegulatory T cells (Treg cells) are controlled by a raft of transcription factors besides Forkhead box protein 3 (FOXP3). As detailed in this Review, these accessory transcription factors act alone or together with FOXP3 to coordinate Treg cell specification and function, and account for heterogeneity of niche-specific Treg cells.
Lire la suite »
SunRay Kelley wanted to build in rhythm with nature, his teacherHis beard was long, his scruffy clothes were matted with mud and straw, and he went barefoot, even in snow. At times, his form seemed more animal than human
Lire la suite »