The chromosome associated with male development, which is the last mysterious piece of the human genome, has been fully sequenced by a team of more than 100 researchers around the world including Johns Hopkins University scientists.
The Y chromosome, along with the X chromosome, is often discussed for its role in sexual development. While these chromosomes play a central role, the factors involved in human sexual development are spread across the genome and very complex, giving rise to the array of human sex characteristics found among male, female and intersex individuals. These categories are not equivalent to gender, which is a social category.
However that work was done with two X chromosomes. Now, using a donor with both an X and a Y chromosome, the consortium built a complete blueprint of the Y chromosome and every element of its DNA. "The genome is a very personal thing, it has the basic instructions for the building blocks of our development and what makes us human," said co-author Rajiv McCoy, a Johns Hopkins assistant professor of biology."We knew we had an incomplete picture up until now, but we can now see the entire genome from end to end for the first time."
Belgique Dernières Nouvelles, Belgique Actualités
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