A Review published in Crit_Care discusses the important pathogenesis and current therapeutic strategies for heat stroke-induced liver injury. The authors suggest targeting the liver for precise treatment along with systematic and supportive treatment.
]. Although a large number of clinical and basic medical researches on HS have been carried out in recent years, most of the underlying pathological mechanisms have not been precisely understood due to the complexity of HS. In the current clinical practice of HS treatment, more systemic treatments such as plasma exchange and hypothermia are used, but specific treatments for HS-induced ALI are lacking.
At present, the research on HS is mainly limited by two aspects. One is the complex pathological mechanism of HS. Secondly, although the incidence rate of HS is increasing year by year [], the number of patients with HS, especially those with severe multiple organ dysfunction and even death, is still relatively less. Therefore, at present, there is no large cohort of clinical studies to provide accurate evidence-based medical evidence for the pathogenesis and treatment of HS.
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