What are the characteristics of misdiagnosed human mpox cases? TelAvivUni Mpox MpoxInfection Infection Misdiagnosis
By Tarun Sai LomteDec 21 2022Reviewed by Aimee Molineux In a recent study published in the International Journal of Infectious Diseases , researchers characterized overlooked cases of mpox .
Around 30% of MPX cases show a concurrent sexually-transmitted infection . MPX represents a new disease in regions that are not endemic and could present a spectrum of clinical features, including those similar to an STI. MPX can be easily overlooked or misdiagnosed as many physicians are unfamiliar with it, leading to delays in diagnosis, isolation, and treatment.
Related StoriesOnly patients diagnosed by a polymerase chain reaction test were included. Overall, 26 patients were included who self-identified as MSM with a history of sexual contact. These subjects were not enquired about contact with an MPX patient during their primary examination by the physician. Five patients were positive for human immunodeficiency virus , and 17 were on HIV pre-exposure prophylaxis .
Six MPX cases were initially misdiagnosed as having bacterial tonsilitis, six as having syphilis, five as herpes, and four as proctitis. Misdiagnosing physicians included primary/emergency care physicians, dermatologists, and proctologists. Twenty-one physicians, who were emergency/primary care physicians or infectious disease specialists, correctly diagnosed MPX. The mean duration between missed and correct diagnosis was 4.4 days.
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