What is the impact of SARS-CoV-2 variant booster vaccinations? medrxivpreprint UofR SARSCoV2 COVID19 Booster Vaccination
By Shanet Susan AlexJul 19 2022Reviewed by Aimee Molineux In a recent study posted to the medRxiv* preprint server, researchers conducted preliminary assessments of booster vaccinating with the severe acute respiratory syndrome coronavirus 2 variant vaccines.
While more booster doses of the existing COVID-19 vaccines, which target the S protein of the SARS-CoV-2 prototype Wuhan-1 strain, might increase vaccine efficacy against VOCs in the near run, variant-specific vaccines might be required for long-lasting and enhanced protection against both known and arising VOCs.
Neutralization antibody titers or infectious dose 50 were evaluated for Beta, Delta, D614G, and Omicron BA.1 variant and Omicron BA.4/BA.5 and BA.2.12.1 subvariants 15 days following vaccination. In addition, on Day 15, a subset of samples from non-SARS-CoV-2-infected individuals in four arms was examined in a separate lab for neutralizing antibody titers to D614G and Omicron BA.2.12.2, BA.1, and BA.4/BA.5 subvariants.
The neutralizing potency against Omicron BA.1 was improved with repeated doses of mRNA vaccines, although the titers remained three to eight times lower than the neutralization of the D614G strain. Omicron-harboring vaccines showed a higher serological reaction against the Omicron BA.1 variant than Prototype.
Belgique Dernières Nouvelles, Belgique Actualités
Similar News:Vous pouvez également lire des articles d'actualité similaires à celui-ci que nous avons collectés auprès d'autres sources d'information.
Study results encourage SARS-CoV-2–infected mothers breastfeed to protect infants from COVIDStudy results encourage SARS-CoV-2–infected mothers breastfeed to protect infants from COVID Antibodies ChildHealth Coronavirus Disease COVID SARSCoV2 breastmilk cordblood newborn pregnant glycoprotein
Lire la suite »
Analyzing whether SARS-CoV-2 nucleocapsid and spike proteins stimulate dendritic or γδ T cellsAnalyzing whether SARS-CoV-2 nucleocapsid and spike proteins stimulate dendritic or γδ T cells tcddublin SARSCoV2 COVID19 Spike DendriticCells
Lire la suite »
Scientists evaluate immunostimulatory glycolipid against SARS-CoV-2 infectionA new study showed that 7DW8-5, an immunostimulatory glycolipid impeded three respiratory viral infections, including SARS-CoV-2, in vivo.
Lire la suite »
Study shows that older adults can generate robust, long-lived memory against SARS-CoV-2 following infectionStudy shows that older adults can generate robust, long-lived memory against SARS-CoV-2 following infection SARSCoV2 infection COVID19 coronavirus covid immunity HSN_Sudbury thenosm UConn LancetLongevity
Lire la suite »
Study suggests COVID-19 vaccination may be associated with short-term changes in usual menstrual cycle lengthStudy suggests COVID-19 vaccination may be associated with short-term changes in usual menstrual cycle length HarvardChanSPH michiganstateu harvardmed BrighamWomens vaccine vaccination COVID19 coronavirus covid menstrualcycle menstruation
Lire la suite »
What is the impact of lower COVID-19 vaccine doses in younger cohorts?What is the impact of lower COVID-19 vaccine doses in younger cohorts? UofCalifornia SARSCoV2 COVID19 Vaccine Children Adolescents
Lire la suite »