Lung cancer's molecular features shed light on immunotherapy response broadinstitute NatureGenet
A.R. is a founder, equity owner, and consultant at Halo Solutions and has served as a consultant at Tyra Biosciences. J.F.G.
is a consultant for Shattuck Labs, Pierre-Fabre, EMD Serono, Clinica Alemana de Santiago, Genmab, Takeda, Merck Sharpe & Dohme, Bristol Myers Squibb, AstraZeneca, Agenus and Torque Therapeutics and receives research funding from Navigate Biopharma, Tesaro/GSK, Moderna Inc., Takeda, Surface Oncology, Pierre-Fabre Research Institute, Merck Sharpe & Dohme, Bristol Myers Squibb, AstraZeneca, Ribon Therapeutics, Akoya Biosciences, Boehringer Ingelheim and Eli Lilly. V.E.V.
Belgique Dernières Nouvelles, Belgique Actualités
Similar News:Vous pouvez également lire des articles d'actualité similaires à celui-ci que nous avons collectés auprès d'autres sources d'information.
Type I interferon shapes brain distribution and tropism of tick-borne flavivirus - Nature CommunicationsHere the authors combine a multimodal imaging-snRNAseq transcriptomics strategy to provide insight into the distribution of a neurotropic tick-borne flavivirus in the brain, and show that absence of interferon signaling increases infection of resident microglia.
Lire la suite »
Circadian clock molecule REV-ERBα regulates lung fibrotic progression through collagen stabilization - Nature CommunicationsThe molecular clock REV-ERBα regulates lung injury during fibrosis, but the role of REV-ERBα in fibrogenesis remains unknown. Here, the authors show that REV-ERBα interacts with the lysyl oxidase-collagen axis during fibrogenesis and demonstrate the therapeutic potential of Rev-erbα agonist against lung fibrosis.
Lire la suite »
ST3GAL1 and βII-spectrin pathways control CAR T cell migration to target tumors - Nature ImmunologyCAR T cell success requires targeting tumors, but these cells can get trapped in other tissues, such as in the lungs, where they can cause pathology. Here, the authors use a loss-of-function CRISPR screen to identify regulators of CAR T cell tumor trafficking and engineer CAR T cells accordingly to overcome this limitation.
Lire la suite »
North Yorkshire: Final public screening of nature-based archive footageThe film charts the changes in environmental views and the natural landscape over 120 years.
Lire la suite »
North Yorkshire: Final public screening of nature-based archive footageIt is the culmination of a year-long series of Beyond Carbon events hosted by North Yorkshire Libraries. Read more:
Lire la suite »