The evidence on ketogenic diets (KDs) from the past three decades.
By Tarun Sai LomteAug 24 2023Reviewed by Lily Ramsey, LLM In a recent study published in the Nutrients Journal, researchers summarized the evidence on ketogenic diets from the past three decades.
Moreover, caution is advised due to the potential possibility of pancreatitis, vascular changes, and cardiac abnormalities. Several studies suggest that KD affects the levels of neurotransmitters involved in seizure onset. For instance, gamma-aminobutyric acid activity might increase in those following a KD.
Additionally, several trials have shown the effectiveness of KD in obesity treatment. Meta-analyses have reported the benefits of a low-carbohydrate diet on weight loss. Moreover, higher ketone body levels could inhibit the NLR family pyrin domain containing 3 inflammasome, limiting inflammation. However, clinical trials assessing the efficacy of KDs in pediatric cancer patients are lacking.
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