Patterns in the Alzheimer's disease (AD) trajectory using Mendelian randomization (MR) and deep learning (DL).
By Pooja Toshniwal PahariaOct 3 2023Reviewed by Lily Ramsey, LLM In a recent study published in eClinical Medicine, researchers analyzed disease progression to identify distinct patterns in the Alzheimer's disease trajectory using Mendelian randomization and deep learning .
About the study In the present study, researchers developed and validated a novel DL-based model to assess the risk of progression through different stages of cognitive decline. A Mendelian randomization study was also conducted to evaluate the causal associations between the identified patterns and Alzheimer's disease development.
Only clinical characteristics with less than 30% missing data in every dataset were included to guarantee that useful clinical features were chosen. The chosen ADNI participants had 1.5 and 3.0 T magnetic resonance imaging data retrieved.
Belgique Dernières Nouvelles, Belgique Actualités
Similar News:Vous pouvez également lire des articles d'actualité similaires à celui-ci que nous avons collectés auprès d'autres sources d'information.
Study indicates possible link between chronic stress and Alzheimer's diseaseResearchers from Karolinska Institutet have published a study in Alzheimer's Research & Therapy that addresses possible associations between chronic stress, mild cognitive impairment and Alzheimer's disease. The study shows how people aged between 18 and 65 with a previous diagnosis of chronic stress and depression were more likely than other people to be diagnosed with mild cognitive impairment or Alzheimer's disease.
Lire la suite »
Microglial states and their impact on Alzheimer's diseaseResearchers examined 152,459 microglial transcriptomes from 443 individuals, identifying 12 transcriptional states and their relationship to Alzheimer's disease.
Lire la suite »
Novel vaccine lowers LDL cholesterol independent of statinsThe effectiveness of virus-like particle (VLP)-based vaccines targeting epitopes in the low-density lipoprotein (LDL) receptor.
Lire la suite »
Do Cormoran Strike and Robin Ellacott finally get together in latest Strike novel, The Running Grave?Robin and Cormoran have been will-they-won’t-they for seven novels now, but do they finally get together in The Running Grave?
Lire la suite »
Mexico’s gangs could be the country’s fifth-biggest employerA recent paper suggests a novel way to curb their power
Lire la suite »
' I don't think it becomes a psychological thing but we've got a lot to learn' - Sam Cosgrove on another Oakwell defeatSome patterns are starting to emerge in Barnsley's League One campaign but forward Sam Cosgrove is not worried that the negative ones could do psychological damage.
Lire la suite »