Obstructive sleep apnea (OSA) consists of multiple episodes of partial or complete closure of the upper airway that occur during sleep, leading to breathing cessation lasting more than ten seconds and sometimes even several minutes, followed by arousals and deep breathing.
A study conducted at the Federal University of São Paulo in Brazil shows that the telomere shortening that naturally occurs with aging and is accelerated by OSA can be mitigated by the use of continuous positive airway pressure , a method of respiratory therapy in which air is pumped into the lungs through the nose and mouth during spontaneous breathing.
In monthly visits, they checked adherence to CPAP, considered complex and hard to get used to. They tookto measure telomere length at the start of the trial, three months later and at the end of the intervention. They also analyzed inflammatory and oxidative stress markers. "The results underscore the criticality of sleep as a protective factor in aging and a risk factor in patients with alterations. This is an excellent incentive since most people are reluctant to use CPAP," said Sergio Tufik , last author of the article and head of UNIFESP's Sleep Institute.A pioneer of sleep research in Brazil and worldwide, Professor Tufik created the Episono project to investigate sleep epidemiology.
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