Patients with atopic dermatitis, the most common inflammatory skin disease in the general population, often have vascular changes that lead to a loss of proteins in their skin and symptoms like oozing, bleeding, infection and redness. In a recent study, researchers at National Jewish Health tested a medication known as dupilumab in patients suffering from this condition. The study found that the drug also helped treat eczema by decreasing the proteins leaking from patients' blood vessels into their inflamed skin.
"Treatment of eczema is imperative, because patients with this disease have a leaky skin barrier, which allows allergens to come in through the skin," said Donald Leung, MD, Ph.D.
, head of Pediatric Allergy & Clinical Immunology at National Jewish Health and first author of the paper published in"Allergens coming through the skin barrier can lead to a condition we refer to as the atopic march.
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