The impact of multimorbidity, smoking status, and demographics on vaccine hesitancy among pregnant women in Wales

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The impact of multimorbidity, smoking status, and demographics on vaccine hesitancy among pregnant women in Wales
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The impact of multimorbidity, smoking status, and demographics on vaccine hesitancy among pregnant women in Wales medrxivpreprint SwanseaUni unibirmingham morbidity vaccine vaccination vaccinehesitancy covid coronavirus

By Tarun Sai LomteDec 19 2022Reviewed by Danielle Ellis, B.Sc. A recent study posted to medRxiv* examined the impact of multimorbidity and smoking on coronavirus disease 2019 vaccine hesitancy among pregnant individuals.

Notwithstanding the mounting evidence on the safety and efficacy of COVID-19 vaccines in pregnant individuals, vaccine hesitancy continues and remains high. The decisions related to vaccination may be influenced by various factors, including multimorbidity, health-related behaviors , and demographic characteristics .

The researchers collected data on vaccination, maternal age, ethnicity, smoking status, cardiovascular disease , diabetes, depression, asthma, and WIMD 2019. Pregnant individuals were excluded if they 1) were fully vaccinated before pregnancy, 2) lacked information on gestational age, or 3) had miscarriage or stillbirth outcomes.

Findings The research team identified 28,343 pregnant individuals between April 13 and December 31, 2021. Of these, 3,232 subjects were double-vaccinated before pregnancy and, thus, excluded from the analysis. Throughout this time frame, 8,203 subjects were vaccinated with at least one dose during pregnancy, 8,336 were vaccinated after delivery, and 8,572 remained non-vaccinated.

Vaccine acceptance was significantly lower among former and current smokers than never-smokers. Individuals aged 30 – 50 were more likely to vaccinate than those in the 25 – 29-year age group. Vaccine acceptance was lower among individuals in most deprived areas than those in affluent areas.

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