The weight loss jabs, sold under the brand names Ozempic, Wegovy and Rybelsus, are set to rollout on the NHS and could improve the symptoms of heart failure in obese patients
and Rybelsus – to treat overweight people with a condition called heart failure with preserved ejection fraction .
The median age of the group was 69 and the median weight was 105.1kg – that ranges from a BMI of 31 for someone 6′ tall to 45 for someone just over 5′ tall. One group was given a once-weekly semaglutide 2.4 mg for one year while the other was given a placebo. The researchers said the improvements were three times greater than the effects seen with any other previous drugs for heart failure, and that this would lead to a “paradigm shift” in how heart failure treatment was approached around the world.
The study was sponsored by Wegovy maker Novo Nordisk, which published its own findings from a five-year study on the drug earlier this month, showing the drug also cuts heart attacks and strokes by a fifth.. The Select trial included 17,604 adults over the age of 45 from across 41 countries, each with a BMI of 27 and over, established cardiovascular disease, and no history of diabetes.
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