Drug-induced nail disorders are uncommon adverse reactions that can occur as a result of drugs. This article will provide an overview of drug-induced nail disorders as well as treatment options. nails naildisorder health
By Marzia KhanReviewed by Sophia Coveney Drug-induced nail disorders are uncommon adverse reactions that can occur as a result of drugs, with nail abnormalities being due to acute damage to the nail unit leading to symptoms associated with the corresponding nail structure. This article will provide an overview of drug-induced nail disorders as well as treatment options.
Additionally, the distal part of the nail matrix includes the protruding white crescent shape that is usually cut once overgrown, with the average nail growth rate comprising 3 mm per month for fingernails and 1 mm per month for toenails. This growth rate can be impacted by different factors such as age, systemic diseases and drugs.
Beau’s lines are clinically seen as deep indentations that run from one side of the nail to the other. The depth of the groove is associated with the level of toxicity in the matrix keratinocytes. Related StoriesOnycholysis includes the separation of the nail plate and the nail bed, and this can sometimes cause nail loss.
Ischemic changes or even necrosis can also occur due to altered blood flow to nails, with Raynaud’s phenomenon being the start of digital ischemia causing fingers to become cold before gangrene development without the return of blood flow. This type of nail disorder can be associated with systemic non-selective beta-blockers and symptoms may be permanent even after treatment discontinuation, with the possibility of finger amputations.
More specifically, onychomadesis has been associated with the following drugs, hydantoin, trimethadione and valproic acid.
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