Does carrot-derived rhamnogalacturonan I positively impact gut microbiota composition and function? Nutrients_MDPI carrot microbiome gut gutmicrobiome composition function guthealth health
Apr 28 2023 In a recent study published in the journal Nutrients, researchers used a novel, ex vivo Systemic Intestinal Fermentation Research ® technology to assess the selectivity with which carrot-derived rhamnogalacturonan I impacted the human gut microbiota.
Though the classification of gut microbiota in distinct gut enterotypes is evolving in gut microbiota research, researchers are aware that Prevotella, Bacteroides, and Ruminococcus are the three top contributors to the microbiota variation in healthy individuals. On the contrary, the high throughput technology used in this study enabled the inclusion of 24 human adults in the study design, which helped the researchers compare the specificity of cRG-I with inulin and xanthan , two traditional prebiotics with low and high specificities, respectively.
Specifically, they extracted short-chain fatty acids , propionate, butyrate, acetate, and valerate, and branched-chain fatty acids . The team compared the treatment effects of the NSC and test compounds using repeated measures ANOVA and Benjamini–Hochberg’s method [False Discovery Rate =0.05)] corrected p-values.
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