Mapping the neuralactivity in mammalian brains CommsBio
cell becomes active. Efforts are being made to elucidate the network structure of neurons by estimating the connections between them from the co-activity of simultaneously recorded neurons. These, however, only showed a visible part of the greater picture that reveals the state of functional neural circuits responsible for driving animal cognition and behavior.
"To reveal the hidden connections from unobserved neurons, we used an analytic relation for nonlinearity between input and output of neurons. We showed it is possible to identify the hidden microcircuits architecture including unobserved neurons, from co-activities of observed neurons," says corresponding author Safura Rashid Shomali of School of Cognitive Sciences at IPM.
"We have learned that the similarity in behavior of people, or neurons, indicates their shared history. Here, behavior is the neuron's activity, and history is the hidden shared inputs they receive," says a co-author S. Nader Rasuli of Department of Physics at University of Guilan and IPM.
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